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Neoplasia Vocab

Neoplasia Vocab

Last update 

Foundation Pathology

Items (59)

  • Cell cycle stage that needs to be alert

    metaphase

  • control switch for cell cycle

    cyclin

  • enzyme that control cyclin

    cyclin dependent kinase (CDK)

  • protein that blocks S phase in cell cycle

    p27

  • protein for DNA repair in cell cycle

    p53

  • do not resemble normal tissue of origin

    anaplasia

  • variation in size, shape, staining of nucleus in malignant tumour

    pleomorphic

  • study of cancer

    oncology

  • benign thyroid cancer

    thyroid adenoma

  • malignant thyroid cancer

    thyroid adenocarcinoma

  • benign smooth muscle cancer

    fibroleiomyoma

  • benign cartilage cancer

    chondroma

  • malignant cartilage cancer

    chondrosacroma

  • malignant glandular cancer

    adenocarcinoma

  • malignant glandular cancer (not resembling original cell)

    anaplastic adenocarcinoma

  • loss of appetite

    anorexia

  • weight loss, anorexia, body mass decrease

    cachexia

  • cellular comparsion of malignant cell

    fetal marker, less intracellular attachment

  • 4 tissue types with no benign tumour

    lymph node, lymphoblast, myeloblast, glia

  • germ cell tumour

    teratoma

  • retinoblastoma/neuroblastoma etc.

    embroynoic cell tumour

  • open exploration (microscopic diagnosis)

    laparotomy

  • tumour marker

    cytokeratin

  • prostate tumour marker

    prostate-specific antigen, prostate specific acid phosphate

  • embryonic cell marker

    carcinoembryonic antigen (CEA)

  • separate patient into diff. groups

    epidemiology

  • no. of new registered case over specific time in defined population

    incidence

  • no. of all (new+old) with defined population at defined time

    prevalence

  • no. of death during specific period in defined population

    mortality

  • 3 types of carcinogen

    phy chem bio

  • DNA repair casuing cancer belong to which type of carcinogen

    physical

  • tobacco and fungi from peanuts cause what cabcer

    lung/skin

  • dye cuases what cancer

    bladder (ciculation!)

  • food addictive contain what compound

    nitrosamine 亞硝胺

  • nitrosamine contributes to what cancer?

    intestine cancer

  • fat leads to what cancer?

    colon cancer

  • fungus causes what cancer

    liver

  • parasite causes what cancer

    urinary bladder

  • rice fluke

    bile dut or liver

  • source of activation of cellular oncogenes

    proto-oncogenes

  • metaphor for tumor suppressor gene

    Police

  • 2 examples of tumor suppressor gene

    RB1, P53

  • WT-1 gene, responsible for Wilms' tumor, is in which organ

    kidney

  • breast cancer gene

    BRCA1, BRCA2

  • smooth muscle tumor

    leiomyoma

  • local expansion tumor without incading basement membrane

    carcinoma in situ

  • growth of vessels into tumor

    angiogenesis

  • 2 tumor angiogenic factors

    chemotactic factors, enzyme

  • common sites of metastasis

    lung, brain, bone, liver

  • enzyme that helps spread cells more efficiently

    proteolytic cell

  • systemic effects related to cancer

    paraneoplastic syndromes

  • tumours that immune system cannot recognize

    tumor invasion

  • T in TNM

    size of tumor

  • N in TNM

    presence of lymph node metastasis

  • M in TNM

    distant metastasis

  • use of own immune cells to regress spotanelously the tumor

    immunotherapy

  • breast changes after 30 yo

    fibrosis & cystic changes

  • immflammation of breast tissues of a mother

    acute mastitis during lactation

  • surgery to cut the whole breast

    mastectomy