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Immunity Vocab

Immunity Vocab

Last update 

Week 4

Items (55)

  • defense mechanism that protects the host from foreign and potentially harmful agent


  • primitive, non-specific immunity

    innate immunity

  • complex cellular and humoral reactions immunity

    adaptive immunity

  • soluble factors


  • blood cell development


  • cells for blood cell development

    stem cells,precursor cells,blast cells,committed cells

  • with packets of toxins


  • examples of granulocytes

    eosinophil, basophil, PMN

  • examples of agranulocytes

    small lymphocytes, monocytes

  • cells that act as a messenger btn innate and adapative immune system

    dendritic cells

  • innate memory


  • characteristics of immune response

    distinguish non-self, invader(specificity), memory(anamnesis),amplification

  • intial infection timeline

    0-4: innate effectors, 4-96:effectors activation, >96:T/B activation

  • reinfection timeline

    Ab + T/B cells

  • influenza immune response

    Day0: PMN,NK,Mo; Day5:muscosal Ab; Day10:T,serum Ab

  • immune response

    natural/artificial + active/passive

  • cascade of protein bind to foreign body

    complement system (soluble mediator)

  • casacde of protein bind to platelets

    coagulation system (soluble mediator)

  • cells in innate immuntiy

    neutrophil, macrophage, NK, complement, lysozyme

  • cells in adaptive immunity

    lymphycote, plasma cells, antigen-presenting cell(APC)

  • plasma cell

    produce antibody

  • effector molecule

    immunogloblin (Ig)

  • T cell activation process


  • 2 types of T cells

    T helper (CD4), cytotxic T (CD8)

  • use of T helper cell

    help B cell produce antibody

  • HIV attack what cell

    CD4 (T helper cell)

  • 3 functions of antibody

    lysis, enhanced phagocytosis, sticking of pathogens

  • antibody lysis

    Ab attach to pathogen and drill holes on them

  • antibody enhanced phagocytosis

    Ab attached to pathogen, easier for macrohpages to phagocytosis

  • antibody sticking the small pathogens

    easier to be detected by macrophages

  • IgM

    largest, first to appear

  • IgG

    smallest, copious

  • IgA

    mucosal secretions

  • IgE

    allergic reaction mediator

  • IgD

    not released (membrance-bounded)

  • reaction of antibody w/ RBC antigen

    agglutination, haemolysis

  • Hypersensitivity - Type 1 - cells involved

    IgE,mast cell,basophil

  • another name for Type 1 hypersensitivity

    anaphylactic (allergy)

  • Hypersensitivity - Type II - cells involved

    cytotoxic, IgG/IgM, complement

  • Hypersensitivity - Type III - cells involved

    immune complex

  • Hypersensitivity - Type Iv - cells involved

    no antobodies

  • Type I hypersensitivity process

    macrophage,B lymphocyte, plasma(IgE),mast cell(histamine)

  • histamine

    smooth muscle contraction, increased vascular permeability causing edema

  • bronchus narrows and muscus blocking the way

    stridor, wheezing,, bronchospasm

  • urticaria


  • Type II hypersensitivity process

    IgG binds to target cell, causing complement lysis and cytotoxicity

  • Type II hypersensitivity leads to two reactions

    lysis, cytotoxicity

  • haemolytic anaemia

    anaemia caused by haemolysis

  • Graves' Disease

    antibody production --> bind to thyroid system

  • Myasthenia Gravis

    antibody targeting to nerve

  • vasculitis

    immune complexes deposit on vessel walls, causing PMNs attack

  • glomerulonephritis

    immune complex deposit on glomerular basment membrane, affecting podocyte

  • complement activation leads to

    vasopermeability leading to edema, smooth muscle contraction

  • lupus

    systemic disease, affecting many parts of body

  • 3 types of disease because of Type III

    lupus, glomerulonephritis, vasulitis